The laboratory analyzes tumor tissue to help diagnose and characterize cancers.

Most tumors are tested using Next Generation Sequencing (NGS).

Other molecular tests include:

• Detecting mutations in individual genes, e.g., EGFR (lung), BRAF (colon), IDH (brain) using qPCR or Idylla tests.

• Analyzing monoclonal T- or B-cells in lymphoid tissue (PCR pattern analysis).

Gene panels used regularly (2026):

• Archer VariantPlex Expanded Solid Tumor Panel (76 genes)

• Archer FusionPlex Sarcoma v2 Panel (63 genes)

• Archer FusionPlex Lung v2 Panel (17 genes)

Panels under setup (Spring 2026):

• Archer Immunovers TCR

• Archer Immunovers BCR

• Archer FusionPlex Lymphoma (125 genes)

• Archer VariantPlex Lymphoma (51 genes)

• Archer VariantPlex HRD Module

Contacts for more information:

• Rósa Björk Barkardóttir – Head of Molecular Pathology, rosa@landspitali.is

• Bylgja Hilmarsdóttir, bylgjahi@landspitali.is

• Gunnhildur Ásta Traustadóttir, gunasta@landspitali.is

• Inga Reynisdóttir, ingar@landspitali.is